Any adverse events following vaccination can be reported to the Vaccine Adverse Event Reporting System (VAERS). According to the CDC, the risk of shingles is approximately 2 to 4 times higher among people with autoimmune disorders. They help us to know which pages are the most and least popular and see how visitors move around the site. People with a history of severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine or after a previous dose of Shingrix. Simberkoff MS, Arbeit RD, Johnson GR, Oxman MN, Boardman KD, et al. It is caused by the varicella-zoster virus (VZV), the same virus that causes chickenpox. 2014 Aug 22; 63(33):729-731. You will be subject to the destination website's privacy policy when you follow the link. It also causes chickenpox. Common side effects, such as soreness and redness at the injection site, are usually mild to moderate in intensity and resolve quickly on their own. Cookies used to make website functionality more relevant to you. Manufacturer: Emergent BioDefense Operations Lansing LLC, amino acids, vitamins, inorganic salts, sugars, proteins [including the 83kDa protective antigen (PA) protein], aluminum, benzethonium chloride, formaldehyde, glycerin, asparagine, citric acid, potassium phosphate, magnesium sulfate, iron ammonium citrate. Consider delaying vaccination if your patient is pregnant, lactating, or experiencing an acute episode of shingles. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. 2016:375(11), 1019-32. Centers for Disease Control and Prevention. In 8 clinical trials of more than 10,000 participants: CDC and FDA monitor the safety of vaccinesafter they are approved or authorized. NEJM. For more information, see Report an Adverse Event to VAERS. J Intern Med. Shingrix is a vaccine indicated for prevention of herpes zoster (HZ) (shingles): in adults aged 50 years and older. You should still get the second dose of recombinant shingles vaccine even if you had one of these reactions after the first dose. The rash consists of blisters that typically scab over in 7 to 10 days and clears up within 2 to 4 weeks. Vaccine Information Statement Tell your provider if you feel dizzy or have vision changes or ringing in the ears. Cabbage moth and fall armyworm cells are used to grow viruses for vaccines. Manufacturer: Wyeth Pharmaceuticals, Inc. E. coli, fermentation growth media, polysorbate 80 (PS80), polysorbate 80, Al+ as AlPO4, histidine buffered saline, Meningococcal Polysaccharide Vaccine, Groups A, C, Y and W-135 Combined, Menomune-A/C/Y/W-135 Package Insert (Mar. While Shingrix is not contraindicated in immunocompromised people, the Advisory Committee on Immunization Practices (ACIP) at this time does not recommend it for this population. 2012 Jan 20;30(5):904-10. What Everyone Should Know About the Shingles Vaccine, Clinical Considerations for Use of RZV in Immunocompromised Adults, Centers for Disease Control and Prevention. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. While both shingles vaccines are safe and effective, they are different in their composition, effectiveness, and potential side effects. Tiredness, muscle pain, headache, shivering, fever, stomach pain, and nausea are common after recombinant shingles vaccine. An older adult with shingles is more likely to develop PHN and have longer lasting and more severe pain than a younger person. Hep A & Hep B (hepatitis A & hepatitis B), 24. People with minor illnesses, such as a cold, may be vaccinated. Tdap Vaccine(tetanus, diphtheria, & pertussis), Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed, Stainer-Scholte medium, casamino acids, dimethylbeta-cyclodextrin, glutaraldehyde, formaldehyde, aluminum phosphate, Mueller-Miller casamino acid medium without beef heart infusion, ammonium sulfate, modified Muellers growth medium, aluminum phosphate, formaldehyde, glutaraldehyde, 2-phenoxyethanol, water, modified Latham medium derived from bovine casein, Fenton medium containing a bovine extract, formaldehyde, modified Stainer-Scholte liquid medium, glutaraldehyde, aluminum hydroxide, aluminum hydroxide, sodium chloride, formaldehyde, polysorbate 80 (Tween 80), Manufacturer: Pfizer Ireland Pharmaceuticals, chick embryo fibroblast (CEF) cells, formaldehyde, sucrose gradient, aluminum hydroxide, human serum albumin, aluminum hydroxide, sodium chloride, dibasic sodium phosphate, monobasic potassium phosphate, formaldehyde, sucrose, protamine sulfate, chick protein, DNA from CEF cells, neomycin, gentamicin, gelatin capsules, sucrose, ascorbic acid, amino acid mixture, lactose, magnesium stearate, Typhoid Vaccine Live Oral TTyphoid Vi Polysaccharide Vacciney21a, semisynthetic medium, casein derived raw materials, hexadecyltrimethylammonium bromide, formaldehyde, formaldehyde, phenol, polydimethylsiloxane, fatty-acid ester-based antifoam, isotonic phosphate buffered saline, sodium chloride, disodium phosphate, monosodium phosphate, water, Varivax Refrigerator Package Insert (undated), Frozen: human embryonic lung cell cultures, embryonic guinea pig cell cultures, human diploid cell cultures (WI-38), Refrigerator: human embryonic lung cell cultures, embryonic guinea pig cell cultures, human diploid cell cultures (WI-38), Frozen: sucrose, phosphate, glutamate, processed gelatin, sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride. 2021), ProQuad Refrigerated Package Insert (Oct. 2018), Refrigerator-Stable Formulation: chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen Formulation Recombinant Human Albumin (RHA): embryo cell culture; WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen Formulation Human SerumAlbumin (HSA): chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen: chick embryo cell culture, WI-38 human diploid lung, MRC-5 cells, Refrigerated: chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Refrigerator-Stable Formulation: sucrose, hydrolyzed gelatin, urea, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components of MRC-5 cells including DNA and protein, neomycin, bovine serum albumin, other buffer and media ingredients, Frozen Formulation Recombinant Human Albumin (RHA): sucrose, hydrolyzed gelatin, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, recombinant human albumin, sodium bicarbonate, potassium phosphate monobasic, potassium chloride; potassium phosphate dibasic, residual components of MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients, Frozen Formulation Human SerumAlbumin (HSA): sucrose, hydrolyzed gelatin, urea, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components of MRC-5 cells including DNA and protein, neomycin, bovine serum albumin, other buffer and media ingredients, Frozen: sucrose, hydrolyzed gelatin, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, recombinant human albumin, sodium bicarbonate, potassium phosphate monobasic, potassium chloride, potassium phosphate dibasic, residual components from the manufacturing process [MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients], Refrigerated: sucrose, sorbitol, hydrolyzed gelatin, urea, sodium chloride, sodium phosphate, monosodium L-glutamate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components from the manufacturing process [MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients], Meningococcal (Groups A, C, Y, and W-135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine, Manufacturer: GlaxoSmithKline Biologicals SA, Franz Complete medium, formaldehyde, CY medium [yeast extracts, amino acids], Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine, Mueller Hinton agar, Watson Scherp media [casamino acid], modified culture medium [hydrolyzed casein], formaldehyde, ammonium sulfate, sodium phosphate buffered isotonic sodium chloride solution, formaldehyde, Manufacturer: Novartis Vaccines and Diagnostics, Inc, Escherichia coli, deoxycholate, aluminum hydroxide, Neisserial adhesin A (NadA), Neisserial Heparin Binding Antigen (NHBA), factor H binding protein (fHbp), outer membrane vesicles (OMV), aluminum hydroxide, sodium chloride, histidine, sucrose, kanamycin. Shingles is more common in older adults, people who have medical conditions that weaken the immune system, and people who take medications that suppress their immune systems. Many people also feel tired or have muscle pain, a headache, shivering, fever, stomach pain, or nausea. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Shingles (also called herpes zoster) is the disease caused when the chickenpox virus reactivates. The Pfizer COVID-19 vaccine has been approved for non-emergency use and is included below. CDC twenty four seven. Shingrix is also recommended for adults 19 years and older who have weakened immune systems because of disease or therapy. The Vaccine Adverse Event Reporting System (VAERS) is an early warning system, co-managed by CDC and FDA, that monitors for potential vaccine safety problems. Centers for Disease Control and Prevention. All information these cookies collect is aggregated and therefore anonymous. Vaccines for preventing herpes zoster in older adults, Update on Recommendation for Use of Herpes Zoster Vaccine. Answer: The Canadian Immunization Guide provides a list of ingredients for all approved vaccines in Canada. Shingrix is the preferred vaccine to prevent shingles. Get CDCs official recommended immunization schedules for children, adolescents, and adults. "Vaccine Ingredients and Manufacturer Information." Shingrix is administered in two doses, usually two to six months apart. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Hum Vaccin. Side effects are more common in younger people. Contact the Centers for Disease Control and Prevention (CDC): The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Shingles vaccination is the only way to protect against shingles and postherpetic neuralgia (PHN), the most common complication from shingles. Saccharomyces cerevisiae cells, aluminum hydroxide, listyeast protein. DTaP-IPV Vaccine(diphtheria, tetanus, pertussis, & polio), Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine. Both Shingrix and Zostavax shingles vaccines have been shown to be safe and well tolerated. Shingrix is safe and effective for most people. ProCon.org is the institutional or organization author for all ProCon.org pages. ", ProCon.org. 2012 Oct 17;10:CD008858. By preventing shingles, recombinant shingles vaccine also protects against PHN and other complications. Report clinically important adverse events that occur after vaccination, even if you are not sure whether the vaccine caused the adverse event, to the Vaccine Adverse Events Reporting System (vaers.hhs.gov). ProCon.org. Antigens can be considered the active ingredients in vaccines because they are the parts of the vaccine to which an immune response is generated. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Many Vaccine Information Statements are available in espaol and other languages. About 1 out of every 3 people in the United States will develop shingles in their lifetime. Antivirals that can treat shingles include: acyclovir valacyclovir famciclovir Additionally, there are many home remedies people can try to help alleviate discomfort. Severe allergic reactions to Shingrix are very rare. MMWR. Safety of herpes zoster vaccine in the shingles prevention study: A randomized trial. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Saving Lives, Protecting People, Shingles vaccination is the only way to protect against, National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services. aluminum hydroxide, sodium chloride, phosphate buffers [disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate], Hepatitis B Vaccine (Recombinant), Adjuvanted, Manufacturer: Dynavax Technologies Corporation, Hansenula polymorpha yeast, fermentation media [vitamins, mineral salts], CpG 1018 adjuvant [22-mer phosphorothioate linked oligodeoxynucleotide, phosphate buffered saline (sodium chloride, sodium phosphate, dibasic dodecahydrate, monobasic dihydrate, polysorbate 80)], yeast protein, yeast DNA, deoxycholate, CpG 1018, Human Papillomavirus Quadrivalent (Types 6, 11, 16, 18) Vaccine, Recombinant, Saccharomyces cerevisiae, fermentation media [vitamins, amino acids, mineral salts, carbohydrates], amorphous aluminum hydroxyphosphate sulfate, amorphous aluminum hydroxyphosphate sulfate adjuvant, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water, Human Papillomavirus 9-valent Vaccine, Recombinant, amorphous aluminum hydroxyphosphate sulfate, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water, Human Papillomavirus Bivalent (Types 16, 18) Vaccine, Recombinant, serum-free culture media [lipids, vitamins, amino acids, mineral salts], hydroxide salt, AS04 [3-O-desacyl-4-monophosphoryl lipid A (MPL), hydroxide salt, sodium chloride, sodium dihydrogen phosphate dihydrate, water, 3-O-desacyl-4-monophosphoryl lipid A (MPL), aluminum hydroxide, sodium chloride, sodium dihydrogen phosphate dihydrate, insect cell and viral protein, bacterial cell protein, 19. 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